{"id":12568,"date":"2024-06-16T01:24:11","date_gmt":"2024-06-15T16:24:11","guid":{"rendered":"https:\/\/jyakusyadansei.com\/?p=12568"},"modified":"2024-06-22T11:03:03","modified_gmt":"2024-06-22T02:03:03","slug":"%e3%80%90%e3%82%a2%e3%82%af%e3%83%aa%e3%83%ab%e3%82%a2%e3%83%9f%e3%83%89%e3%80%91%e3%82%a4%e3%83%b3%e3%82%b9%e3%82%bf%e3%83%b3%e3%83%88%e3%82%b3%e3%83%bc%e3%83%92%e3%83%bc%e3%81%ae%e6%bd%9c%e5%9c%a8","status":"publish","type":"post","link":"https:\/\/jyakusyadansei.com\/?p=12568","title":{"rendered":"\u3010\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u3011\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306e\u6f5c\u5728\u30ea\u30b9\u30af\u3001\u598a\u5a20\u4e2d\u306b\u7279\u306b\u6ce8\u610f\u3001\u767a\u304c\u3093\u30ea\u30b9\u30af\u3042\u308a"},"content":{"rendered":"
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\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306f\u3001\u98df\u54c1\u304c\u9ad8\u6e29\u3067\u8abf\u7406\u3055\u308c\u308b\u969b\u306b\u751f\u6210\u3055\u308c\u308b\u5316\u5b66\u7269\u8cea\u3067\u3042\u308a\u3001\u767a\u304c\u3093\u6027\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306b\u306f\u7279\u306b\u9ad8\u6fc3\u5ea6\u306e\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u304c\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u554f\u984c\u8996\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30b3\u30fc\u30d2\u30fc\u305d\u306e\u3082\u306e\u306b\u3082\u5065\u5eb7\u30ea\u30b9\u30af\u3068\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u304c\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n

\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u30ea\u30b9\u30af\u306b\u52a0\u3048\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u5065\u5eb7\u30ea\u30b9\u30af\u3068\u5229\u70b9\u306b\u3064\u3044\u3066\u6700\u65b0\u306e\u7814\u7a76\u3092\u57fa\u306b\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002\u7279\u306b\u598a\u5a20\u4e2d\u306e\u30b3\u30fc\u30d2\u30fc\u6442\u53d6\u306b\u3064\u3044\u3066\u3082\u89e6\u308c\u307e\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u5316\u5b66\u69cb\u9020\u3068\u751f\u6210\u904e\u7a0b<\/h2>\n

\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u5316\u5b66\u69cb\u9020<\/h3>\n

\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\uff08\u5316\u5b66\u5f0f: C_3H_5NO\uff09\u306f\u3001\u9ad8\u53cd\u5fdc\u6027\u306e\u6709\u6a5f\u5316\u5408\u7269\u3067\u3042\u308a\u3001\u30e2\u30ce\u30de\u30fc\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u7121\u81ed\u306e\u767d\u8272\u7d50\u6676\u6027\u56fa\u4f53\u3067\u3001\u6c34\u3001\u30a8\u30bf\u30ce\u30fc\u30eb\u3001\u30a8\u30fc\u30c6\u30eb\u3001\u30af\u30ed\u30ed\u30db\u30eb\u30e0\u306b\u6eb6\u3051\u307e\u3059\u3002\u5206\u5b50\u69cb\u9020\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\uff1a<\/p>\n

    \n
  • \u5206\u5b50\u5f0f: C_3H_5NO<\/li>\n
  • \u69cb\u9020\u5f0f: CH2=CH-CONH2<\/li>\n<\/ul>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u751f\u6210\u904e\u7a0b<\/h3>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306f\u3001\u98df\u54c1\u304c\u9ad8\u6e29\u3067\u8abf\u7406\u3055\u308c\u308b\u969b\u306b\u30a2\u30b9\u30d1\u30e9\u30ae\u30f3\u3068\u9084\u5143\u7cd6\u306e\u9593\u3067\u767a\u751f\u3059\u308b\u30de\u30a4\u30e9\u30fc\u30c9\u53cd\u5fdc\u3092\u901a\u3058\u3066\u751f\u6210\u3055\u308c\u307e\u3059\u3002\u7279\u306b\u3001\u63da\u3052\u7269\u3001\u713c\u304d\u83d3\u5b50\u3001\u30d1\u30f3\u3001\u30c8\u30fc\u30b9\u30c8\u3001\u305d\u3057\u3066\u30b3\u30fc\u30d2\u30fc\u306a\u3069\u306e\u70ad\u6c34\u5316\u7269\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306b\u591a\u304f\u898b\u3089\u308c\u307e\u3059 (Soares et al., 2015)\u3002<\/p>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u5065\u5eb7\u30ea\u30b9\u30af<\/h2>\n

    \u767a\u304c\u3093\u6027<\/h3>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306f\u52d5\u7269\u5b9f\u9a13\u3067\u767a\u304c\u3093\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u4eba\u9593\u306b\u5bfe\u3057\u3066\u3082\u540c\u69d8\u306e\u30ea\u30b9\u30af\u304c\u61f8\u5ff5\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u56fd\u969b\u304c\u3093\u7814\u7a76\u6a5f\u95a2 (IARC) \u306f\u3001\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u3092\u300c\u30d2\u30c8\u306b\u5bfe\u3057\u3066\u304a\u305d\u3089\u304f\u767a\u304c\u3093\u6027\u304c\u3042\u308b (\u30b0\u30eb\u30fc\u30d72A)\u300d\u3068\u5206\u985e\u3057\u3066\u3044\u307e\u3059 (Semla et al., 2017)\u3002<\/p>\n

    \u305d\u306e\u4ed6\u306e\u5065\u5eb7\u30ea\u30b9\u30af<\/h3>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306f\u3001\u795e\u7d4c\u6bd2\u6027\u3084\u751f\u6b96\u6bd2\u6027\u3082\u6301\u3064\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30ea\u30b9\u30af\u306f\u3001\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u304c\u4f53\u5185\u3067\u4ee3\u8b1d\u3055\u308c\u3001\u30b0\u30ea\u30b7\u30c9\u30a2\u30df\u30c9\uff08GA\uff09\u306b\u5909\u63db\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002GA\u306f\u3001\u907a\u4f1d\u5b50\u6bd2\u6027\u304a\u3088\u3073\u767a\u304c\u3093\u6027\u3092\u6301\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059 (Schouten et al., 2020)\u3002<\/p>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u5065\u5eb7\u30ea\u30b9\u30af<\/h2>\n

    \u5fc3\u8840\u7ba1\u75be\u60a3<\/h3>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u6d88\u8cbb\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e00\u90e8\u306e\u7814\u7a76\u3067\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u304c\u8840\u5727\u3092\u4e0a\u6607\u3055\u305b\u3001\u8840\u4e2d\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 (O\u2019Keefe et al., 2013)\u3002<\/p>\n

    \u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af<\/h3>\n

    \u598a\u5a20\u4e2d\u306e\u5973\u6027\u306b\u3068\u3063\u3066\u3001\u904e\u5270\u306a\u30b3\u30fc\u30d2\u30fc\u6442\u53d6\u306f\u65e9\u7523\u3084\u4f4e\u51fa\u751f\u4f53\u91cd\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u598a\u5a20\u4e2d\u306f1\u65e53\u30ab\u30c3\u30d7\u4ee5\u5185\u306b\u5236\u9650\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059 (Higdon & Frei, 2006)\u3002<\/p>\n

    \u305d\u306e\u4ed6\u306e\u30ea\u30b9\u30af<\/h3>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u904e\u5270\u6442\u53d6\u306f\u3001\u4e0d\u5b89\u3001\u5931\u7720\u3001\u982d\u75db\u3001\u632f\u6226\u3001\u52d5\u60b8\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u5973\u6027\u306b\u304a\u3044\u3066\u306f\u9aa8\u6298\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059 (O\u2019Keefe et al., 2018)\u3002<\/p>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u5229\u70b9<\/h2>\n

    \u7cd6\u5c3f\u75c5\u4e88\u9632<\/h3>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u6d88\u8cbb\u306f\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u306e\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u52b9\u679c\u306f\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3001\u30af\u30ed\u30ed\u30b2\u30f3\u9178\u3001\u305d\u306e\u4ed6\u306e\u751f\u7269\u6d3b\u6027\u5316\u5408\u7269\u306b\u3088\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059 (Bidel & Tuomilehto, 2013)\u3002<\/p>\n

    \u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u4e88\u9632<\/h3>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u5b9a\u671f\u7684\u306a\u6442\u53d6\u306f\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3084\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306a\u3069\u306e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u52b9\u679c\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u306b\u542b\u307e\u308c\u308b\u6297\u9178\u5316\u7269\u8cea\u3068\u6297\u708e\u75c7\u6027\u6210\u5206\u306b\u8d77\u56e0\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059 (G\u00f6kcen & Sanlier, 2019)\u3002<\/p>\n

    \u809d\u81d3\u4fdd\u8b77<\/h3>\n

    \u30b3\u30fc\u30d2\u30fc\u306e\u6d88\u8cbb\u306f\u3001\u809d\u81d3\u306e\u5065\u5eb7\u306b\u3082\u826f\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u809d\u786c\u5909\u3084\u809d\u7d30\u80de\u764c\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059 (Saab et al., 2014)\u3002<\/p>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u5f71\u97ff\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u5bfe\u7b56<\/h2>\n

    \u8abf\u7406\u65b9\u6cd5\u306e\u5de5\u592b<\/h3>\n

    \u98df\u54c1\u5168\u822c\u306b\u304a\u3044\u3066\u3001\u713c\u304d\u3059\u304e\u306a\u3044\u3088\u3046\u306b\u3057\u3001\u9069\u5207\u306a\u6e29\u5ea6\u3068\u6642\u9593\u3067\u8abf\u7406\u3059\u308b\u3053\u3068\u304c\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u751f\u6210\u3092\u6291\u3048\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u63da\u3052\u7269\u306e\u5834\u5408\u3001\u4f4e\u6e29\u3067\u63da\u3052\u308b\u304b\u3001\u63da\u3052\u6642\u9593\u3092\u77ed\u304f\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059 (Friedman, 2015)\u3002<\/p>\n

    \u30b3\u30fc\u30d2\u30fc\u306b\u304a\u3051\u308b\u5bfe\u7b56<\/h3>\n

    \u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306b\u6bd4\u3079\u3001\u30ec\u30ae\u30e5\u30e9\u30fc\u30b3\u30fc\u30d2\u30fc\u306e\u65b9\u304c\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306e\u542b\u6709\u91cf\u304c\u5c11\u306a\u3044\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u6709\u6a5f\u683d\u57f9\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u9078\u3076\u3053\u3068\u3001\u6d45\u714e\u308a\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u9078\u3076\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059 (Granby & Fagt, 2004)\u3002<\/p>\n

    \u7d50\u8ad6<\/h2>\n

    \u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9\u306f\u3001\u7279\u5b9a\u306e\u98df\u54c1\u304c\u9ad8\u6e29\u3067\u8abf\u7406\u3055\u308c\u308b\u969b\u306b\u751f\u6210\u3055\u308c\u308b\u5316\u5b66\u7269\u8cea\u3067\u3042\u308a\u3001\u7279\u306b\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\u30b3\u30fc\u30d2\u30fc\u306b\u306f\u9ad8\u6fc3\u5ea6\u3067\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u5065\u5eb7\u30ea\u30b9\u30af\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u305f\u3081\u306b\u306f\u3001\u30ec\u30ae\u30e5\u30e9\u30fc\u30b3\u30fc\u30d2\u30fc\u3084\u6709\u6a5f\u683d\u57f9\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u9078\u3073\u3001\u6d45\u714e\u308a\u306e\u30b3\u30fc\u30d2\u30fc\u3092\u98f2\u3080\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u6dfb\u52a0\u7269\u3092\u907f\u3051\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u30b3\u30fc\u30d2\u30fc\u305d\u306e\u3082\u306e\u306b\u306f\u3001\u5065\u5eb7\u306b\u5bfe\u3059\u308b\u30ea\u30b9\u30af\u3068\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306e\u4e21\u65b9\u304c\u5b58\u5728\u3057\u3001\u7279\u306b\u598a\u5a20\u4e2d\u306f\u6442\u53d6\u91cf\u306b\u6ce8\u610f\u3059\u308b\u3053\u3068\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

    \u53c2\u8003\u6587\u732e<\/h3>\n
      \n
    • Soares, C., Alves, R. C., & Oliveira, M. B. (2015). Acrylamide in Coffee: Influence of Processing<\/span><\/li>\n
    • Mes\u00edas, M., & Morales, F. (2016). Acrylamide in coffee: Estimation of exposure from vending machines<\/span><\/li>\n
    • Narita, Y., & Inouye, K. (2014). Decrease in the acrylamide content in canned coffee by heat treatment with the addition of cysteine<\/span><\/li>\n
    • Schouten, M., Tappi, S., & Romani, S. (2020). Acrylamide in coffee: formation and possible mitigation strategies \u2013 a review<\/span><\/li>\n
    • Granby, K., & Fagt, S. (2004). Acrylamide in Food<\/span><\/li>\n
    • [Friedman, M. (2015). Chemistry, Biochemistry, and Safety<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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